Eflornithine hydrochloride Monohydrate ( DFMO | Eflornithine )

产品货号. M16851 CAS No. 96020-91-6

盐酸依氟鸟氨酸水合物（DFMO；MDL-71782）是一种可有效治疗面部多毛症的化合物。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
50MG	￥243	有现货
100MG	￥340	有现货
200MG	￥470	有现货
500MG	￥1004	有现货
1G	获取报价	有现货

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生物学信息

产品名称

Eflornithine hydrochloride Monohydrate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

盐酸依氟鸟氨酸水合物（DFMO；MDL-71782）是一种可有效治疗面部多毛症的化合物。
产品描述

Eflornithine hydrochloride, hydrate (DFMO; MDL-71782) is a drug found to be effective in the treatment of facial hirsutism.(In Vivo):Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.
体外实验

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体内实验

Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.
同义词

DFMO | Eflornithine
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靶点

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受体

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研究领域

Other Indications
适应症

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